| Saltheril's Haven Party Invitation | Physical | 3 sec cast |
| Salvage Wreckage | Physical | 2 sec cast |
| Sample Ley Line Field | Physical | 5 sec cast |
| Sanctified Judgement Rank 1 | Physical | Instant |
| Sanctified Judgement Rank 2 | Physical | Instant |
| Sanctified Judgement Rank 3 | Physical | Instant |
| Sanctified Light Rank 1 | Physical | Instant |
| Sanctified Light Rank 2 | Physical | Instant |
| Sanctified Light Rank 3 | Physical | Instant |
| Sanctified Orb | Holy | Instant |
| Sanctified Seals Rank 1 | Physical | Instant |
| Sanctified Seals Rank 2 | Physical | Instant |
| Sanctified Seals Rank 3 | Physical | Instant |
| Sanctity Aura | Holy | Instant |
| Sanctuary | Physical | Instant |
| Sandstalker Bracers | Physical | 45 sec cast |
| Sandstalker Breastplate | Physical | 45 sec cast |
| Sandstalker Gauntlets | Physical | 45 sec cast |
| Santos' Blessing | Frost | Instant |
| Sap Rank 2 | Physical | Instant |
| Sap Rank 3 | Physical | Instant |
| Sap Rank 1 | Physical | Instant |
| Sapphire Pendant of Winter Night | Physical | 45 sec cast |
| Sapphire Signet | Physical | 45 sec cast |
| Sapta Sight | Physical | Instant |
| Sapta Sight | Physical | Instant |
| Sapta Sight | Physical | Instant |
| Sapta Sight | Physical | Instant |
| Sapta Sight | Physical | Instant |
| Satchel of Cenarius | Physical | 50 sec cast |
| Savage Fury Rank 1 | Physical | Instant |
| Savage Fury Rank 2 | Physical | Instant |
| Savage Guard | Physical | 4 sec cast |
| Savage Strikes Rank 1 | Physical | Instant |
| Savage Strikes Rank 2 | Physical | Instant |
| Savior's Sacrifice | Physical | Instant |
| Savory Deviate Delight | Physical | 3 sec cast |
| Scaled Draenic Boots | Physical | 25 sec cast |
| Scaled Draenic Gloves | Physical | 25 sec cast |
| Scaled Draenic Pants | Physical | 25 sec cast |
| Scaled Draenic Vest | Physical | 25 sec cast |
| Scare Beast Rank 1 | Nature | 1.5 sec cast |
| Scare Beast Rank 2 | Nature | 1.5 sec cast |
| Scare Beast Rank 3 | Nature | 1.5 sec cast |
| Scarlet Illusion | Arcane | Instant |
| Scatter Shot | Physical | Instant |
| Scooby Snack Effect | Physical | Instant |
| Scorch Rank 1 | Fire | 1.5 sec cast |
| Scorch Rank 8 | Fire | 1.5 sec cast |
| Scorch Rank 9 | Fire | 1.5 sec cast |