| Unleashed Rage Rank 4 | Physical | Instant |
| Unleashed Rage Rank 5 | Physical | Instant |
| Unleashed Rage Rank 2 | Physical | Instant |
| Unleashed Rage Rank 3 | Physical | Instant |
| Unleashed Rage Rank 4 | Physical | Instant |
| Unleashed Rage Rank 5 | Physical | Instant |
| Unlock Maury's Foot | Physical | 5 sec cast |
| Unlocking | Physical | 5 sec cast |
| Unlocking | Physical | 5 sec cast |
| Unlocking Zuluhed's Chains | Physical | 5 sec cast |
| Unpainted Mechanostrider | Physical | 3 sec cast |
| Unrelenting Storm Rank 1 | Physical | Instant |
| Unrelenting Storm Rank 2 | Physical | Instant |
| Unrelenting Storm Rank 3 | Physical | Instant |
| Unrelenting Storm Rank 4 | Physical | Instant |
| Unrelenting Storm Rank 5 | Physical | Instant |
| Unstable Affliction | Shadow | Instant |
| Unstable Affliction Rank 1 | Shadow | 1.5 sec cast |
| Unstable Affliction Rank 2 | Shadow | 1.5 sec cast |
| Unstable Affliction Rank 3 | Shadow | 1.5 sec cast |
| Unstable Flask of the Bandit | Physical | Instant |
| Unstable Flask of the Beast | Physical | Instant |
| Unstable Flask of the Elder | Physical | Instant |
| Unstable Flask of the Physician | Physical | Instant |
| Unstable Flask of the Soldier | Physical | Instant |
| Unstable Flask of the Sorcerer | Physical | Instant |
| Unstable Mana Potion | Physical | 3 sec cast |
| Unstable Power | Physical | Instant |
| Unstable Trigger | Physical | 3 sec cast |
| Unsummon Sanctified Crystal | Physical | Instant |
| Untamed Fury | Physical | Instant |
| Unyielding Bracers | Physical | 45 sec cast |
| Unyielding Faith Rank 2 | Physical | Instant |
| Unyielding Faith Rank 1 | Physical | Instant |
| Unyielding Girdle | Physical | 50 sec cast |
| Unyielding Knights | Holy | Instant |
| Use Bauble | Physical | 3 sec cast |
| Use Broom | Physical | 3 sec cast |
| Use Filled Brewfest Stein | Physical | Instant |
| Use Filled Brewfest Stein | Physical | Instant |
| Use Filled Brewfest Stein | Physical | Instant |
| Use Filled Brewfest Stein | Physical | Instant |
| Use Filled Brewfest Stein | Physical | Instant |
| Use Mirren's Drinking Hat | Physical | Instant |
| Using Direbrew's Remote | Physical | 10 sec cast |
| Using Jump-a-tron 4000 | Physical | 5 sec cast |
| Using Steam Tonk Controller | Physical | Channeled |
| Uther's Light Rank 1 | Physical | Instant |
| Uther's Tribute | Physical | 2 sec cast |
| Uttering the Words of Damnation | Physical | 20 sec cast |